Prevalence and risk factors associated with Hepatitis B virus coinfection with HIV amon patients attending some selected hospitals in Kaduna metropolis

Authors

  • A.M. Aliyu Kaduna Polytechnic, Department of Applied Science, College of Science and Technology. PMB 2021, Kaduna, Nigeria
  • Maryam Aliyu Yakasai Kaduna Polytechnic, Department of Applied Science, College of Science and Technology. PMB 2021, Kaduna, Nigeria
  • Afusat Bola Rufai Kaduna Polytechnic, Department of Applied Science, College of Science and Technology. PMB 2021, Kaduna, Nigeria

Keywords:

Hepatitis B virus, Human immunodeficiency virus, Co-infection, Prevalence

Abstract

300 blood samples were analyzed for the presence of Hepatitis B surface antigen (HBsAg), using smart checkTM HBsAg strip. 270 were HIV positive while 30 were HIV negative patients. Out of the 270 HIV positive patients 35 (13.0%) were HBsAg positive while out of the 30 HIV negative patients 1 (3.3%) was HBsAg positive. Prevalence was highest in age group 15-20 (25.0%) with zero prevalence in age group below 15 and above 51 in HIV positive patients, there is significant statistical association between age and the occurrence of HBV infection (P<0.05). Higher prevalence was recorded in males 16.2% than females 11.7%, there is no significant association between the occurrence of HBV and sex (P>0.05). Multiple sex partners have the highest prevalence (50.0%) and no sex partner have the lowest prevalence (5.3%).This reveals that patients that are HIV positive are at risk of contracting HBV infection.

References

Alter, M.J., 2006. Epidemiology of viral Hepatitis and HIV co infection. J. Hepatol. 44(1sppl), 56-59.

Fix, O.K., Locarmini, S.A., Peters, M.G., 2007. Virology and clinical management of Hepatitis B and HIV co-infection. Physician. Res. Network. 11.

Hamza, M., Samaila, A.A., Yakasai, A.M., Babashani, M., Borodo, M.M., Habib A.G., 2013. Prevalence of Hepatitis B and C virus infections among HIV infected patients in a tertiary hospital in North-western Nigeria, 10(2), 76-78.

Jawetz, Melnic, Adelberg’s, 2007. Medical Microbiology. In: Geo, F. B., Kacen, C.C., Janet, S.B. Stephen, A.M., 23rd International Edition, Mcgraw Hill Publisher, 550 – 569.

Mahoney, F.J., 1999. Update on diagnosis, management and prevention of Hepatitis B virus infection. Clin. Microbiol. Rev. 12, 351-366.

Pouti, M., Manno, D., Nasta, P., Carosi, G., 2008. Hepatitis B virus and HIV co-infection in low-income countries: Unmet Needs. Clin. Infect. Dis. 46, 367-369.

Rouet, F., Chaix, M.L., Inwoley, D., Anaky, M-F., Fissinou, P., Kpozehouen, A., Rouzioux, C., Blanche, S., Msellati, P., 2008. Chronic Hepatitis B virus (HBV) infections among West African human immunodeficiency Virus Type 1- infected children. Clin. Infect. Dis. 46, 361-366.

Sadoh, A.E., Sadoh, W.E., Iduoriyekemwen, N.J., 2011. HIV co-infection with Hepatitis B and C viruses among Nigerian children in an antiretroviral treatment programme. South. Afr. J. Child. Health. 5(suppl1), 7-10.

Sarka, J., Bandyopadhyay, B., Chakrabarty, R., Bhattacharya, N., Adhikan, S., Mondal, S., Mukherjee, A., Guha, S.K., 2013. HIV-HBV co-infection among individuals attending the ICTC of a tertiary care hospital in West Bengal India. Int. Sch. Res. Not. Virol.

Toukan, A., 1990. Strategy for the control of hepatitis B virus infection in the Middle East and North Africa. Vaccine. 8, S117-S121.

Uneke, C.J., Ogbu, O., Inyama, P.U., Anyanwu, G.I., Njoku, M.O., Idoko, J.H., 2005. Prevalence of Hepatitis B surface antigen among blood donors and Human Immunodeficiiency Virus infected patients in Jos, Nigeria. Memorias do instituto osswaldo cruz, 100(1), 13-16.

Published

2015-10-29

How to Cite

A.M. Aliyu, Maryam Aliyu Yakasai, & Afusat Bola Rufai. (2015). Prevalence and risk factors associated with Hepatitis B virus coinfection with HIV amon patients attending some selected hospitals in Kaduna metropolis. Scientific Journal of Pure and Applied Sciences, 4(10), 193-199. Retrieved from http://sjournals.com/index.php/sjpas/article/view/285

Issue

Section

Biological Sciences