The histopathological effects of salvia officinalis on the kidney and liver of rats

Authors

  • D. A. Adekomi Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria
  • T. D. Adeniyi Department of Anatomy, College of Medicine, Osun State University, Osogbo, Osun State, Nigeria
  • A. M. Afodun Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria
  • K. K. Quadri Department of Physiology, University of Lagos, Lagos, Nigeria

Keywords:

Kidney, Liver, Normal saline, Histopathology, Sprague-Dawley Rats

Abstract

The aim of this investigationwas to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old)were randomly assigned into two groups; A and B. Aqueous extract of S.officinalis leaves (300 mg/kg body weight) was administered orally to therats in group B while the rats in group A received equal volume of normalsaline for 14d. At termination of treatment, the histopathology of the kidneyand liver were assessed. The kidney and the liver in the extract treated ratdisplayed organized and preserved histological profile. Our findings suggestthat S. officinalis has no deleterious effects on the kidney and liverof the rats.

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Published

2013-03-27

How to Cite

A. Adekomi, D. ., D. Adeniyi, T., M. Afodun, A., & K. Quadri, K. (2013). The histopathological effects of salvia officinalis on the kidney and liver of rats. Scientific Journal of Medical Science, 2(3), 31-37. Retrieved from http://sjournals.com/index.php/sjms/article/view/1344

Issue

Vol. 2 No. 3 (2013): March

Section

Original Article

License

Copyright (c) 2013 D. A. Adekomi, T. D. Adeniyi, A. M. Afodun, K. K. Quadri

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.