The histopathological effects of salvia officinalis on the kidney and liver of rats

Authors

  • D.A. Adekomi Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria Lecturer, Department of Anatomy
  • A.M. Afodun Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria
  • K.K. Quadri Department of Physiology, University of Lagos, Lagos, Nigeria
  • T.D. Adeniyi Department of Anatomy, College of Medicine, Osun State University, Osogbo, Osun Stat, Nigeria

Keywords:

Kidney, Liver, Normal saline, Histopathology, Sprague-Dawley Rats

Abstract

The aim of this investigation was to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old) were randomly assigned into two groups; A and B. Aqueous extract of S. officinalis leaves (300 mg/kg body weight) was administered orally to the rats in group B while the rats in group A received equal volume of normal saline for 14d. At termination of treatment, the histopathology of the kidney and liver were assessed. The kidney and the liver in the extract treated rat displayed organized and preserved histological profile. Our findings suggest that S. officinalis has no deleterious effects on the kidney and liver of the rats.

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Published

2013-12-28

How to Cite

Adekomi, D. ., Afodun, A. ., Quadri, K. ., & Adeniyi, T. . (2013). The histopathological effects of salvia officinalis on the kidney and liver of rats. Scientific Journal of Biological Sciences, 2(2), 32-38. Retrieved from http://sjournals.com/index.php/sjbs/article/view/1064

Issue

Vol. 2 No. 2 (2013): February

Section

Original Article

License

Copyright (c) 2013 D.A. Adekomi, A.M. Afodun, K.K. Quadri, T.D. Adeniyi

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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