http://sjournals.com/index.php/sjbs <p>Scientific Journal of Biological Sciences (SJBS)is a peer-reviewed and well indexed scientific journal dedicated to publish and disseminate the high quality scientific research work in the broad field of biological sciences. Scope of the journal includes: cell biology, developmental biology, structural biology, microbiology, molecular biology &amp; genetics, biochemistry, biotechnology, biodiversity, ecology, marine biology, plant biology, and bioinformatics.</p> Sjournals en-US Scientific Journal of Biological Sciences 2322-1968 http://sjournals.com/index.php/sjbs/article/view/1723 <p>The emergence and spread of resistance to chemical anthelmintics in gastrointestinal nematode populations has led to the search for alternative solutions such as the use of medicinal plants with anthelmintic properties. This study was undertaken to examine the in vivo effect of <em>Parkia biglobosa</em> and <em>Pterocarpus erinaceus</em> on the viability and fertility of adult <em>Haemonchus contortus</em> worms in sheep. Fifteen Djallonke sheep, 4 to 5 months old, were divided into three experimental lots. The control lot received no treatment. Two lots were treated with 3.2 g/kg PV of plant powder. <em>P. biglobosa</em> significantly reduced egg excretion compared to the control (p &lt; 0.05). Both plants significantly (p &lt; 0.05) reduced the number of adult worms and the number of eggs per female worm. Numbers of adult worms and eggs per female worm were 330.00 ± 112.84 and 332.0 ± 191.9 in the control lot, 17.50 ± 10.41 and 176.0 ± 96.1 in the lot treated with <em>P. biglobosa</em> and 86.25 ± 53.13 and 146.8 ± 90.6 in the lot treated with <em>P. erinaceus</em>, respectively. This study showed that <em>P. biglobosa</em> and <em>P. erinaceus</em> exerted anthelmintic activity in vivo on adult <em>H. contortus</em> worms. Further investigations are needed to evaluate the toxicity of these plants and to understand their metabolism in the digestive tract of animals.</p> Vidjinnangni Fifamè Grâce Nadège Dedehou Irvine Yèïnou Minaflinou Sacca Sidi Fréjus Tanguy Ablo Zinsou Pascal Abiodoun Olounladé Sylvie Mawulé Hounzangbé-Adoté Copyright (c) 2022 Vidjinnangni Fifamè Grâce Nadège Dedehou, Irvine Yèïnou Minaflinou Sacca Sidi, Fréjus Tanguy Ablo Zinsou, Pascal Abiodoun Olounladé, Sylvie Mawulé Hounzangbé-Adoté https://creativecommons.org/licenses/by-nc-nd/4.0 2022-10-22 2022-10-22 11 1 284 292