Mammary Adenocarcinoma in lioness

Authors

  • A. D. Firdous Department of Veterinary Anatomy and Histology, College of Veterinary and Animal Sciences Mannuthy Thrissur - 680651, Kerala, India
  • S. Maya Department of Veterinary Anatomy and Histology, College of Veterinary and Animal Sciences Mannuthy Thrissur - 680651, Kerala, India
  • V. Sunil Kumar Department of Veterinary Anatomy and Histology, College of Veterinary and Animal Sciences Mannuthy Thrissur - 680651, Kerala, India
  • N. D. Nair Department of Veterinary Anatomy and Histology, College of Veterinary and Animal Sciences Mannuthy Thrissur - 680651, Kerala, India
  • N. Ashok Department of Veterinary Anatomy and Histology, College of Veterinary and Animal Sciences Mannuthy Thrissur - 680651, Kerala, India
  • S. Pramod Department of Veterinary Anatomy and Histology, College of Veterinary and Animal Sciences Mannuthy Thrissur - 680651, Kerala, India

Keywords:

anaplastic cells, mammary gland, metastasis

Abstract

A lioness was brought for postmortem at the Wild Animal Rescue Centre, Kodanad Kerala India. The right mammary gland was extremely enlarged and was completely invaded by coalescent yellowish granular masses and whitish connective tissue. Histopathology of the organs revealed proliferation of round or polyhydric mild anaplastic cells, with round hyper chromatic nuclei, evident nucleoli and eosinophilic cytoplasm and with moderate anaplasia. The cells formed solid masses surrounded by fine connective stroma. Mitotic figures were conspicuous and in many areas the tumor cells invaded the blood and lymphatic vessels. There were metastatic changes in the retro-mammary lymph node and other organs of the pelvic, abdominal or thoracic cavities with similar characteristics of primary tumor.

References

McAloose, D., Munson, L., Naydan, D.K., 2007. Histologic features of mammary carcinomas in zoo felids treated with melengestrol acetate (MGA) contraceptives. Vet. Pathol., 44, 320–326.

Harrenstien, L.A., Munson, L., Seal, U.S., et al., 1996. Mammary cancer in captive wild felids and risk factors for its development: a retrospective study of the clinical behavior of 31 cases. J Zoo Wildl Med 27, 468–176.

Lair, S., Barker, I.K., Mehren, K.G., et al., 2002. Epidemiology of neoplasia in captive black-footed ferrets (Mustela nigripes), 1986–1996. J. Zoo. Wildl. Med. 33, 204–213.

Canfield, P.J., Hartley, W.J., Reddacliff, G.L., 1990. Spontaneous proliferations in Australian marsupials -a survey and review. 1. Macropods, koalas, wombats, possums and gliders. J. Comp. Pathol. 103, 135–146.

Munson L., Moresco A., 2007. Comparative Pathology of Mammary Gland Cancers in Domestic and Wild Animals. Breast Disease. 28, 7–21

Kumar V., 2005. Patologia – Bases patológicas das doenças. 7.ed. Rio de Janeiro: Elsevier, 1592p.

Effron, M., Griner L., Benirschke, K., 1977. Nature and rate of neoplasia found in captive wild mammals, birds, and reptiles at necropsy. J. Natl. Cancer Inst., 59, 185–194.

Downloads

Published

2013-03-24

How to Cite

D. Firdous, A., Maya, S. ., Sunil Kumar, V. ., D. Nair, N., Ashok, N. ., & Pramod, S. . (2013). Mammary Adenocarcinoma in lioness. Scientific Journal of Review, 2(3), 103-105. Retrieved from http://sjournals.com/index.php/sjr/article/view/663

Issue

Vol. 2 No. 3 (2013): March

Section

Veterinary Medicine

License

Copyright (c) 2013 A. D. Firdous, S. Maya, V. Sunil Kumar, N. D. Nair, N. Ashok, S. Pramod

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Most read articles by the same author(s)