Cover Image

Anthelmintic potentials of Andrographis paniculata: A preliminary study

Shanthi Subbarayan, Bharathi Vadivel, Rajapandiyan Krishnamoorthy, Ali A Alshatwi


Andrographis paniculata (Acanthaceae), a potential medicinal plant, distributed in waste lands, open forests in  India. A. paniculata is used in the treatment of typhoid, snake bite, scorpion sting, malaria and cancer. The acetone, chloroform and aqueous extracts were evaluated for its anthelmintic activity against adult earth worms (Phertima prosthuma). Three concentrations (10, 50 and 100 mg/ml) of each extract were which involved the determination of time of paralysis and time of death of the test worms. It was found that the acetone and aqueous fraction of Andrographis paniculata of was proved to be one of the best alternative cum effective herbal  remedy to control helminthic infections.


Bundy, D.A., 1994. Immunoepidemiology of intestinal helminthic infection: The global burden of intestinal nematode disease. Trans. Royal Soc. Trop. Med. Hyg., 8, 259-61.

Coles, G.C., 1997. Nematode control practices and anthelmintic resistance on British sheep farms. Vet. Rec., 141, 91-93.

Geert, S., Dorny, P., 1995. Anthelmintic resistance in helminthes of animals of man in the tropics. Bulletin-des-Seances, Academic-Royaledes-Sciencesd. Dutre Mer, 3, 401-423.

Sondhi, S.M., Shahu, R., Magan, A., 1994. Comparative in vitro anthelmintic activity of three plants from the am’aranthaceae family Indian drugs. Biol. Sci., 31(7), 317-320.

Tagbota, S., Townson, S., 2001. Antiparasitic properties of medicinal plants and other naturally occurring products. Adv. Parasitol., 50, 199-295.

Tripathi, K.D., 2003. Essentials of meditional pharmacology. Edn 5th, Jaypee Brothers Medical Publishers (P) LTD., New Delhi, 759.

Full Text: PDF


  • There are currently no refbacks.