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Antimutagenic activity of rosmarinus officinalis l. By Ames test

A. Tajehmiri, M.T. Ghasemi, F.P. Sabet, M.M. Doost Chakoosari, N. Abdolahzadegan


Plants are an important source of substanceswhich are claimed to induce anti-inflammatory and antioxidant effects. Rosemary(Rosmarinus officinalis L.) is a medicinal plant that has many uses intraditional medicine. In this study, of R. officinalis leaves extracts werescreened for their antimutagenic activity against sodium azide by Ames test.The results showed that of R. officinalis leaves extracts can inhibit mutagenicagent of sodium azide. Rosemary leaves extracts with the inhibition of 42.92%sodium azide, showed high potential in decreasing mutagenic agent.Antimutagenic activity was increased significantly when there were livermicrosome extract (S9).


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