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Impact of antioxidants, oxidative stress on gametogenesis, embryogenesis, and fertility in livestock production

Thandolwethu Nyathi

Abstract


Gametogenesis is a fundamental aspect in sexual reproduction. Successful gametogenesis transcends to high fertility in any breeding herd when all other production factors are held optimum. The interaction amongst gametogenesis, embryogenesis, antioxidants and oxidative stress should be considered a key component of livestock fertility which has the potential to improve efficiency. This discussion looks at the influence of antioxidants and oxidative stress on gametogenesis, embryogenesis and livestock fertility in broad. Any disorders during gametogenesis and embryogenesis result in reduced fertility in livestock. Infertility is one of the major bottlenecks hampering livestock production. Livestock fertility is a multi-factorial trait as its decline is attributed to physiological, genetic, and environmental as well as husbandry factors. Furthermore, the discussion will spell out how antioxidants can be exploited as a remedy to tackle negative effects of reactive oxygen species in in vivo.


References


Agarwal, A., Allamaneni, S.S.R., 2004. Oxidants and antioxidants in human fertility. Mid. East. Fert. Soc. J., 9(3), 187-197.

Agarwal, A., Durairajanayagam, D., du Plessis, S.S., 2014. Utility of antioxidants during assisted reproductive techniques: An evidence based review. Reprod. Biol. Endocrinol. RB&E, 12, 112. https://doi.org/10.1186/1477-7827-12-112

Agarwal, A., Gupta, S., Sharma, R., 2005. Oxidative stress and its implications in female infertility - A clinician’s perspective. Reprod. BioMed. Online, https://doi.org/10.1016/S1472-6483(10)61174-1

Ahotupa, M., Huhtaniemi, I., 1992. Impaired detoxification of reactive oxygen and consequent oxidative stress in experimentally cryptorchid rat testis. Biol. Reprod., 46(6), 1114-1118. https://doi.org/10.1095/biolreprod46.6.1114

Al-Gubory, K.H., Fowler, P.A., Garrel, C., 2010. The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes. Int. J. Biochem. Cell Biol., https://doi.org/10.1016/j.biocel.2010.06.001

Al-Qudah, K.M., 2011. Oxidant and antioxidant profile of hyperketonemic ewes affected by pregnancy toxemia. Vet. Clin. Pathol., 40(1), 60-65. https://doi.org/10.1111/j.1939-165X.2011.00284.x

Bedwal, R.S., Bahuguna, A., 1994. Zinc, copper and selenium in reproduction. Experientia, https://doi.org/10.1007/BF01952862

Bobe, J., Labbé, C., 2010. Egg and sperm quality in fish. Gen. Comp. Endocrinol., 165(3), 535-548. https://doi.org/10.1016/j.ygcen.2009.02.011

Castillo, C., Hernandez, J., Bravo, A., Lopez-Alonso, M., Pereira, V., Benedito, J.L., 2005. Oxidative status during late pregnancy and early lactation in dairy cows. Vet. J., 169(2), 286-292. https://doi.org/10.1016/j.tvjl.2004.02.001

Cohen-Kerem, R., Koren, G., 2003. Antioxidants and fetal protection against ethanol teratogenicity: I. Review of the experimental data and implications to humans. Neurotoxicol. Teratol., https://doi.org/10.1016/S0892-0362(02)00324-0

Gaweł, S., Wardas, M., Niedworok, E., Wardas, P., 2004. Malondialdehyde (MDA) as a lipid peroxidation marker. Wiadomości Lekarskie (Warsaw, Poland: 1960), 57(9–10), 453–5. Retrieved from: http://www.ncbi.nlm.nih.gov/pubmed/15765761

Gonçalves, F.S., Barretto, L.S.S., Arruda, R.P., Perri, S.H.V., Mingoti, G.Z., 2010. Effect of antioxidants during bovine in vitro fertilization procedures on spermatozoa and embryo development. Reprod. Domest. Anim., 45(1), 129-135. https://doi.org/10.1111/j.1439-0531.2008.01272.x

Guérin, P., El Mouatassim, S., Ménézo, Y., 2001. Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings. Hum. Reprod. Update, https://doi.org/10.1093/humupd/7.2.175

Hemingway, R.G., 2003. The influences of dietary intakes and supplementation with selenium and vitamin E on reproduction diseases and reproductive efficiency in cattle and sheep. Vet. Res. Comm., https://doi.org/10.1023/A:1022871406335

Koksal, I.T., Usta, M., Orhan, I., Abbasoglu, S., Kadioglu, A., 2003. Potential role of reactive oxygen species on testicular pathology associated with infertility. Asian J. Androl., 5(2), 95-99.

Luddi, A., Capaldo, A., Focarelli, R., Gori, M., Morgante, G., Piomboni, P., De Leo, V., 2016. Antioxidants reduce oxidative stress in follicular fluid of aged women undergoing IVF. Reprod. Biol. Endocrinol., 14(1), https://doi.org/10.1186/s12958-016-0184-7

Marteniuk, J.V., Herdt, T.H., 1988. Pregnancy toxemia and ketosis of ewes and does. Vet. Clin. North Am. Food Anim. Pract., 4(2), 307-315. https://doi.org/10.1016/S0749-0720(15)31050-1

Migaud, H., Bell, G., Cabrita, E., Mcandrew, B., Davie, A., Bobe, J., Carrillo, M., 2013. Gamete quality and broodstock management in temperate fish. Rev. Aquaculture, https://doi.org/10.1111/raq.12025

Moslemi, M.K., Tavanbakhsh, S., 2011. Selenium-vitamin E supplementation in infertile men: Effects on semen parameters and pregnancy rate. Int. J. Gen. Med., 4, 99-104. https://doi.org/10.2147/IJGM.S16275

Oteiza, P.L., Olin, K.L., Fraga, C.G., Keen, C.L., 1996. Oxidant defense systems in testes from zinc-deficient rats. Proc. Soc. Exp. Biol. Med., 213(1), 85-91.

Pintea, A., Zinveliu, D., 2006. Antioxidant status in dairy cows during lactation. Bulletin of University of …, 130-135. https://doi.org/10.15835/buasvmcn-vm:63:1-2:2445

Rurangwa, E., Kime, D.E., Ollevier, F., Nash, J.P., 2004. The measurement of sperm motility and factors affecting sperm quality in cultured fish. Aquaculture, https://doi.org/10.1016/j.aquaculture.2003.12.006

Salami, S.A., Guinguina, A., Agboola, J.O., Omede, A.A., Agbonlahor, E.M., Tayyab, U., 2016. Review: In vivo and postmortem effects of feed antioxidants in livestock: A review of the implications on authorization of antioxidant feed additives. Anim., https://doi.org/10.1017/S1751731115002967

Sies, H., 1997. Oxidative stress: oxidants and antioxidants. Exp. Physiol., 82(2), 291-295. https://doi.org/10.1113/expphysiol.1997.sp004024

Spears, J.W., Weiss, W.P., 2008. Role of antioxidants and trace elements in health and immunity of transition dairy cows. Vet. J., 176(1), 70-76. https://doi.org/10.1016/j.tvjl.2007.12.015

Surai, P., Kostjuk, I., Wishart, G., Macpherson, A., Speake, B., Noble, R., Kutz, E., 1998. Effect of vitamin E and selenium supplementation of cockerel diets on glutathione peroxidase activity and lipid peroxidation susceptibility in sperm, testes, and liver. Biol. Trace Elem. Res., 64, 119-132. https://doi.org/10.1007/BF02783329

Tsunoda, S., Kimura, N., Fujii, J., 2014. Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development. Reprod. Med. Biol., 13(2), 71-79. https://doi.org/10.1007/s12522-013-0170-0

Turner, T.T., Lysiak, J.J., 2008. Oxidative stress: A common factor in testicular dysfunction. J. Androl., https://doi.org/10.2164/jandrol.108.005132


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