In 1977, Haller used the term "metabolic syndrome" for associations of obesity, diabetes mellitus, hyperlipoproteinemia, hyperuricemia, and hepatic steatosiswhen describing the additive effects of risk factors on atherosclerosis (Haller, 1977).
The main sign of metabolic syndrome is central obesity (also known as visceral, male-pattern or apple-shaped adiposity), overweight with adipose tissue accumulation particularly around the waist and trunk.
The term syndrome on basis of the encyclopedic dictionary of the Romanian language defined as group of signs and symptoms that appear together during a pathological process, giving it the characteristic note without knowing the exact cause. The term of syndrome derives from the Greek word sundromos (sun-syn + dromos= to run) and i.e. “to run together”.